Asian Journal of Sports Medicine

Published by: Kowsar

Comparison of Effect of One Course of Intense Exercise (Wingate test) on Serum Levels of Interleukin-17 in Different Groups of Athletes

Asghar Tofighee 1 , Hossein Ali Khazaei 2 , * and Arman Jalili 3
Authors Information
1 Department of Sport Physiology, Urmia University, Urmia, IR Iran
2 Research Center for Children and Adolescents Health, Department of Medical Immunology and Hematology, Zahedan University of Medical Sciences, Zahedan, IR Iran
3 Department of Sport Physiology, Tehran University, Tehran, IR Iran
Article information
  • Asian Journal of Sports Medicine: December 01, 2014, 5 (4); e22769
  • Published Online: September 15, 2014
  • Article Type: Research Article
  • Received: July 22, 2013
  • Accepted: December 27, 2013
  • DOI: 10.5812/asjsm.22769

To Cite: Tofighee A, Khazaei H A, Jalili A. Comparison of Effect of One Course of Intense Exercise (Wingate test) on Serum Levels of Interleukin-17 in Different Groups of Athletes, Asian J Sports Med. 2014 ; 5(4):e22769. doi: 10.5812/asjsm.22769.

Copyright © 2014, Sports Medicine Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Hoffman-Goetz L, Pedersen BK. Exercise and the immune system: a model of the stress response? Immunol Today. 1994; 15(8): 382-7[DOI][PubMed]
  • 2. Nieman DC. Exercise immunology: future directions for research related to athletes, nutrition, and the elderly. Int J Sports Med. 2000; 21 Suppl 1-8[PubMed]
  • 3. Nieman DC. Exercise immunology: practical applications. Int J Sports Med. 1997; 18 Suppl 1-100[DOI][PubMed]
  • 4. Malm C. Exercise immunology: the current state of man and mouse. Sports Med. 2004; 34(9): 555-66[PubMed]
  • 5. Pedersen BK, Nieman DC. Exercise immunology: integration and regulation. Immunol Today. 1998; 19(5): 204-6[PubMed]
  • 6. Shephard RJ. Special feature for the Olympics: effects of exercise on the immune system: overview of the epidemiology of exercise immunology. Immunol Cell Biol. 2000; 78(5): 485-95[DOI][PubMed]
  • 7. Timmons BW. Paediatric exercise immunology: health and clinical applications. Exerc Immunol Rev. 2005; 11: 108-44[PubMed]
  • 8. Smith JA. Guidelines, standards, and perspectives in exercise immunology. Med Sci Sports Exerc. 1995; 27(4): 497-506[PubMed]
  • 9. Bernstein E, Kaye D, Abrutyn E, Gross P, Dorfman M, Murasko DM. Immune response to influenza vaccination in a large healthy elderly population. Vaccine. 1999; 17(1): 82-94[PubMed]
  • 10. Ramson R, Jurimae J, Jurimae T, Maestu J. The influence of increased training volume on cytokines and ghrelin concentration in college level male rowers. Eur J Appl Physiol. 2008; 104(5): 839-46[DOI][PubMed]
  • 11. Robson-Ansley PJ, Blannin A, Gleeson M. Elevated plasma interleukin-6 levels in trained male triathletes following an acute period of intense interval training. Eur J Appl Physiol. 2007; 99(4): 353-60[DOI][PubMed]
  • 12. Maier SF, Watkins LR. Cytokines for psychologists: implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition. Psychol Rev. 1998; 105(1): 83-107[PubMed]
  • 13. Albanesi C, Cavani A, Girolomoni G. IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha. J Immunol. 1999; 162(1): 494-502[PubMed]
  • 14. Melzer N, Meuth SG, Torres-Salazar D, Bittner S, Zozulya AL, Weidenfeller C, et al. A beta-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis. PLoS One. 2008; 3(9)[DOI][PubMed]
  • 15. Moseley TA, Haudenschild DR, Rose L, Reddi AH. Interleukin-17 family and IL-17 receptors. Cytokine Growth Factor Rev. 2003; 14(2): 155-74[PubMed]
  • 16. Zhu X, Mulcahy LA, Mohammed RA, Lee AH, Franks HA, Kilpatrick L, et al. IL-17 expression by breast-cancer-associated macrophages: IL-17 promotes invasiveness of breast cancer cell lines. Breast Cancer Res. 2008; 10(6)[DOI][PubMed]
  • 17. Pischon T, Hu FB, Rexrode KM, Girman CJ, Manson JE, Rimm EB. Inflammation, the metabolic syndrome, and risk of coronary heart disease in women and men. Atherosclerosis. 2008; 197(1): 392-9[DOI][PubMed]
  • 18. Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest. 2006; 116(7): 1793-801[DOI][PubMed]
  • 19. Tsatsanis C, Androulidaki A, Venihaki M, Margioris AN. Signalling networks regulating cyclooxygenase-2. Int J Biochem Cell Biol. 2006; 38(10): 1654-61[DOI][PubMed]
  • 20. Chang SH, Dong C. A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses. Cell Res. 2007; 17(5): 435-40[DOI][PubMed]
  • 21. Duzova H, Karakoc Y, Emre MH, Dogan ZY, Kilinc E. Effects of Acute Moderate and Strenuous Exercise Bouts on IL-17 Production and Inflammatory Response in Trained Rats. J Sports Sci Med. 2009; 8(2): 219-24[PubMed]
  • 22. Golzari Z, Shabkhiz F, Soudi S, Kordi MR, Hashemi SM. Combined exercise training reduces IFN-gamma and IL-17 levels in the plasma and the supernatant of peripheral blood mononuclear cells in women with multiple sclerosis. Int Immunopharmacol. 2010; 10(11): 1415-9[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments