Asian Journal of Sports Medicine

Published by: Kowsar

Resistance Training Decreases Lipid Content of Different Fat Deposits in Ovariectomized Rats

Anderson Diogo de Souza Lino 1 , 2 , * , Richard Diego Leite 3 , Jonato Prestes 4 , Guilherme Borges Pereira 4 , Nuno Sousa Frade 5 , Rodrigo Ferro Magosso 1 , Fernanda de Oliveira Duarte 2 , 7 , Marcela Sene-Fiorese 2 , 6 , Whitley Jo Stone 8 , Ana Claudia Garcia de Oliveira Duarte 2 , Sergio Eduardo de Andrade Perez 1 and Gilberto Eiji Shiguemoto 1
Authors Information
1 Laboratory of Exercise Physiology, Department of Physiological Sciences, Federal University of Sao Carlos, Sao Carlos, SP, Brazil
2 Laboratory of Nutrition and Metabolism Applied to Exercise, Department of Physical Education and Human Motricity, Federal University of Sao Carlos, Sao Carlos, SP, Brazil
3 Department of Physical Education, Federal University of Espirito Santo, Vitoria, ES, Brazil
4 Graduate Program on Physical Education, Catholic University of Brasilia, Brazil.
5 Faculty of Estacio de Sa de Vitoria, Espirito Santo, Brazil
6 Sao Carlos Institute of Physics, University of Sao Paulo USP, PO Box 369, Zip Code 13560-970, Sao Carlos, Brazil;
7 Department of Physiotherapy, Laboratory of Physical Therapy Resources Laboratory, Federal University of Sao Carlos , Sao Paulo, Brazil.
8 Department of Nutrition and Kinesiology, University of Central Missouri, United States of America
Article information
  • Asian Journal of Sports Medicine: March 2018, 9 (1); e62258
  • Published Online: March 2, 2018
  • Article Type: Research Article
  • Received: January 31, 2017
  • Revised: September 27, 2017
  • Accepted: October 30, 2017
  • DOI: 10.5812/asjsm.62258

To Cite: Lino A D D S, Diego Leite R, Prestes J, Borges Pereira G, Sousa Frade N, et al. Resistance Training Decreases Lipid Content of Different Fat Deposits in Ovariectomized Rats, Asian J Sports Med. 2018 ; 9(1):e62258. doi: 10.5812/asjsm.62258.

Abstract
Copyright © 2018, Asian Journal of Sports Medicine. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Asikainen TM, Kukkonen-Harjula K, Miilunpalo S. Exercise for health for early postmenopausal women: a systematic review of randomised controlled trials. Sports Med. 2004;34(11):753-78. [PubMed: 15456348].
  • 2. Babaei P, Mehdizadeh R, Ansar MM, Damirchi A. Effects of ovariectomy and estrogen replacement therapy on visceral adipose tissue and serum adiponectin levels in rats. Menopause Int. 2010;16(3):100-4. doi: 10.1258/mi.2010.010028. [PubMed: 20956683].
  • 3. Barsalani R, Pighon A, Rabasa-Lhoret R, Yasari S, Lavoie JM. Liver of ovariectomized rats is resistant to resorption of lipids. Physiol Behav. 2008;95(1-2):216-21. doi: 10.1016/j.physbeh.2008.05.024. [PubMed: 18590750].
  • 4. Bjorntorp P. Hormonal control of regional fat distribution. Hum Reprod. 1997;12 Suppl 1:21-5. [PubMed: 9403318].
  • 5. Cinti S. The adipose organ. Prostaglandins Leukot Essent Fatty Acids. 2005;73(1):9-15. doi: 10.1016/j.plefa.2005.04.010. [PubMed: 15936182].
  • 6. Corriveau P, Paquette A, Brochu M, Prud'homme D, Rabasa-Lhoret R, Lavoie JM. Resistance training prevents liver fat accumulation in ovariectomized rats. Maturitas. 2008;59(3):259-67. doi: 10.1016/j.maturitas.2008.02.005. [PubMed: 18367352].
  • 7. D'Eon TM, Souza SC, Aronovitz M, Obin MS, Fried SK, Greenberg AS. Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways. J Biol Chem. 2005;280(43):35983-91. doi: 10.1074/jbc.M507339200. [PubMed: 16109719].
  • 8. Toth MJ, Tchernof A, Rosen CJ, Matthews DE, Poehlman ET. Regulation of protein metabolism in middle-aged, premenopausal women: roles of adiposity and estradiol. J Clin Endocrinol Metab. 2000;85(4):1382-7. doi: 10.1210/jcem.85.4.6533. [PubMed: 10770170].
  • 9. Votruba SB, Jensen MD. Regional fat deposition as a factor in FFA metabolism. Annu Rev Nutr. 2007;27:149-63. doi: 10.1146/annurev.nutr.27.061406.093754. [PubMed: 17506663].
  • 10. Iozzo P. Myocardial, perivascular, and epicardial fat. Diabetes Care. 2011;34 Suppl 2:S371-9. doi: 10.2337/dc11-s250. [PubMed: 21525485].
  • 11. Latour MG, Shinoda M, Lavoie JM. Metabolic effects of physical training in ovariectomized and hyperestrogenic rats. J Appl Physiol (1985). 2001;90(1):235-41. doi: 10.1152/jappl.2001.90.1.235. [PubMed: 11133915].
  • 12. Paquette A, Shinoda M, Rabasa Lhoret R, Prud'homme D, Lavoie JM. Time course of liver lipid infiltration in ovariectomized rats: impact of a high-fat diet. Maturitas. 2007;58(2):182-90. doi: 10.1016/j.maturitas.2007.08.002. [PubMed: 17889461].
  • 13. Gerbaix M, Metz L, Ringot E, Courteix D. Visceral fat mass determination in rodent: validation of dual-energy X-ray absorptiometry and anthropometric techniques in fat and lean rats. Lipids Health Dis. 2010;9:140. doi: 10.1186/1476-511X-9-140. [PubMed: 21143884].
  • 14. Du T, Yu X, Zhang J, Sun X. Lipid accumulation product and visceral adiposity index are effective markers for identifying the metabolically obese normal-weight phenotype. Acta Diabetol. 2015;52(5):855-63. doi: 10.1007/s00592-015-0715-2. [PubMed: 25690647].
  • 15. Djibo DA, Araneta MR, Kritz-Silverstein D, Barrett-Connor E, Wooten W. Body adiposity index as a risk factor for the metabolic syndrome in postmenopausal Caucasian, African American, and Filipina women. Diabetes Metab Syndr. 2015;9(2):108-13. doi: 10.1016/j.dsx.2014.04.011. [PubMed: 25470644].
  • 16. Genazzani AR, Gadducci A, Gambacciani M. Controversial issues in climacteric medicine II. Hormone replacement therapy and cancer. International Menopause Society Expert Workshop. 9-12 June 2001, Opera del Duomo, Pisa, Italy. Climacteric. 2001;4(3):181-93. [PubMed: 11588941].
  • 17. Pighon A, Paquette A, Barsalani R, Chapados NA, Rabasa-Lhoret R, Yasari S, et al. Resistance training attenuates fat mass regain after weight loss in ovariectomized rats. Maturitas. 2009;64(1):52-7. doi: 10.1016/j.maturitas.2009.07.005. [PubMed: 19683884].
  • 18. Domingos MM, Rodrigues MF, Stotzer US, Bertucci DR, Souza MV, Marine DA, et al. Resistance training restores the gene expression of molecules related to fat oxidation and lipogenesis in the liver of ovariectomized rats. Eur J Appl Physiol. 2012;112(4):1437-44. doi: 10.1007/s00421-011-2098-6. [PubMed: 21830097].
  • 19. Stotzer US, Rodrigues MF, Domingos MM, Silva GH, Duarte FO, Gatto CV, et al. Resistance training suppresses intra-abdominal fatty acid synthesis in ovariectomized rats. Int J Sports Med. 2015;36(3):226-33. doi: 10.1055/s-0034-1390494. [PubMed: 25415388].
  • 20. Leite RD, Prestes J, Bernardes CF, Shiguemoto GE, Pereira GB, Duarte JO, et al. Effects of ovariectomy and resistance training on lipid content in skeletal muscle, liver, and heart; fat depots; and lipid profile. Appl Physiol Nutr Metab. 2009;34(6):1079-86. doi: 10.1139/H09-116. [PubMed: 20029517].
  • 21. Speretta GF, Rosante MC, Duarte FO, Leite RD, Lino AD, Andre RA, et al. The effects of exercise modalities on adiposity in obese rats. Clinics (Sao Paulo). 2012;67(12):1469-77. [PubMed: 23295603].
  • 22. Hornberger TJ, Farrar RP. Physiological hypertrophy of the FHL muscle following 8 weeks of progressive resistance exercise in the rat. Can J Appl Physiol. 2004;29(1):16-31. [PubMed: 15001801].
  • 23. Figueiredo Braggion G, Ornelas E, Carmona Sattin Cury J, Edviges Alves Lima N, Aquino RC, Affonso Fonseca FL, et al. Morphological and Biochemical Effects on the Skeletal Muscle of Ovariectomized Old Female Rats Submitted to the Intake of Diets with Vegetable or Animal Protein and Resistance Training. Oxid Med Cell Longev. 2016;2016:9251064. doi: 10.1155/2016/9251064. [PubMed: 26885253].
  • 24. do Valle Gomes-Gatto C, Duarte FO, Stotzer US, Rodrigues MFC, de Andrade Perez SE, Selistre-de-Araujo HS. Estrogen deficiency in ovariectomized rats: can resistance training re-establish angiogenesis in visceral adipose tissue?. Clinics. 2016;71(9):528-36.
  • 25. Kalu DN. The ovariectomized rat model of postmenopausal bone loss. Bone Miner. 1991;15(3):175-91. [PubMed: 1773131].
  • 26. Prestes J, de Cassia Marqueti R, Shiguemoto GE, Leite RD, Pereira GB, Selistre-de-Araujo HS, et al. Effects of ovariectomy and resistance training on MMP-2 activity in skeletal muscle. Appl Physiol Nutr Metab. 2009;34(4):700-6. doi: 10.1139/H09-059. [PubMed: 19767806].
  • 27. Leite RD, Durigan Rde C, de Souza Lino AD, de Souza Campos MV, Souza M, Selistre-de-Araujo HS, et al. Resistance training may concomitantly benefit body composition, blood pressure and muscle MMP-2 activity on the left ventricle of high-fat fed diet rats. Metabolism. 2013;62(10):1477-84. doi: 10.1016/j.metabol.2013.05.009. [PubMed: 23790633].
  • 28. Sene-Fiorese M, Duarte FO, Scarmagnani FR, Cheik NC, Manzoni MS, Nonaka KO, et al. Efficiency of intermittent exercise on adiposity and fatty liver in rats fed with high-fat diet. Obesity (Silver Spring). 2008;16(10):2217-22. doi: 10.1038/oby.2008.339. [PubMed: 18719640].
  • 29. Duarte FO, Sene-Fiorese M, Manzoni MS, de Freitas LF, Cheik NC, Garcia de Oliveira Duarte AC, et al. Caloric restriction and refeeding promoted different metabolic effects in fat depots and impaired dyslipidemic profile in rats. Nutrition. 2008;24(2):177-86. doi: 10.1016/j.nut.2007.10.012. [PubMed: 18068950].
  • 30. Stansbie D, Denton RM, Bridges BJ, Pask HT, Randle PJ. Regulation of pyruvate dehydrogenase and pyruvate dehydrogenase phosphate phosphatase activity in rat epididymal fat-pads. Effects of starvation, alloxan-diabetes and high-fat diet. Biochem J. 1976;154(1):225-36. [PubMed: 6018].
  • 31. Shinoda M, Latour MG, Lavoie JM. Effects of physical training on body composition and organ weights in ovariectomized and hyperestrogenic rats. Int J Obes Relat Metab Disord. 2002;26(3):335-43. doi: 10.1038/sj.ijo.0801900. [PubMed: 11896488].
  • 32. Kemmler W, Lauber D, Weineck J, Hensen J, Kalender W, Engelke K. Benefits of 2 years of intense exercise on bone density, physical fitness, and blood lipids in early postmenopausal osteopenic women: results of the Erlangen Fitness Osteoporosis Prevention Study (EFOPS). Arch Intern Med. 2004;164(10):1084-91. doi: 10.1001/archinte.164.10.1084. [PubMed: 15159265].
  • 33. Moran AL, Nelson SA, Landisch RM, Warren GL, Lowe DA. Estradiol replacement reverses ovariectomy-induced muscle contractile and myosin dysfunction in mature female mice. J Appl Physiol (1985). 2007;102(4):1387-93. doi: 10.1152/japplphysiol.01305.2006. [PubMed: 17218423].
  • 34. Shiguemoto GE, Rossi EA, Baldissera V, Gouveia CH, de Valdez Vargas GM, de Andrade Perez SE. Isoflavone-supplemented soy yoghurt associated with resistive physical exercise increase bone mineral density of ovariectomized rats. Maturitas. 2007;57(3):261-70. doi: 10.1016/j.maturitas.2007.01.011. [PubMed: 17368767].
  • 35. Park HS, Lee KU. Postmenopausal women lose less visceral adipose tissue during a weight reduction program. Menopause. 2003;10(3):222-7. [PubMed: 12792294].
  • 36. Shiguemoto GE, Prestes J, Leite RD, Pereira GB, Pontes CL, D'Avila FV, et al. Effects of resistance training on matrix metalloproteinase-2 activity and biomechanical and physical properties of bone in ovariectomized and intact rats. Scand J Med Sci Sports. 2012;22(5):607-17. doi: 10.1111/j.1600-0838.2010.01284.x. [PubMed: 21362057].
  • 37. Feresin RG, Johnson SA, Elam ML, Jo E, Arjmandi BH, Hakkak R. Effects of obesity on bone mass and quality in ovariectomized female Zucker rats. J Obes. 2014;2014:690123. doi: 10.1155/2014/690123. [PubMed: 25309751].
  • 38. Lavoie JM, Gauthier MS. Regulation of fat metabolism in the liver: link to non-alcoholic hepatic steatosis and impact of physical exercise. Cell Mol Life Sci. 2006;63(12):1393-409. doi: 10.1007/s00018-006-6600-y. [PubMed: 16649140].
  • 39. Paquette A, Wang D, Jankowski M, Gutkowska J, Lavoie JM. Effects of ovariectomy on PPAR alpha, SREBP-1c, and SCD-1 gene expression in the rat liver. Menopause. 2008;15(6):1169-75. doi: 10.1097/gme.0b013e31817b8159. [PubMed: 18665039].
  • 40. Paquette A, Chapados NA, Bergeron R, Lavoie JM. Fatty acid oxidation is decreased in the liver of ovariectomized rats. Horm Metab Res. 2009;41(7):511-5. doi: 10.1055/s-0029-1202348. [PubMed: 19241328].
  • 41. Dobrzyn A, Knapp M, Gorski J. Effect of acute exercise and training on metabolism of ceramide in the heart muscle of the rat. Acta Physiol Scand. 2004;181(3):313-9. doi: 10.1111/j.1365-201X.2004.01295.x. [PubMed: 15196092].
  • 42. Donnelly JE, Blair SN, Jakicic JM, Manore MM, Rankin JW, Smith BK, et al. American College of Sports Medicine Position Stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc. 2009;41(2):459-71. doi: 10.1249/MSS.0b013e3181949333. [PubMed: 19127177].
  • 43. Wing RR, Lang W, Wadden TA, Safford M, Knowler WC, Bertoni AG, et al. Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes. Diabetes Care. 2011;34(7):1481-6. doi: 10.2337/dc10-2415. [PubMed: 21593294].
  • 44. Rodrigues MFC, Ferreira FC, Silva-Magosso NS, Barbosa MR, Souza MVC, Domingos MM, et al. Effects of resistance training and estrogen replacement on adipose tissue inflammation in ovariectomized rats. Appl Physiol Nutr Metab. 2017;42(6):605-12. doi: 10.1139/apnm-2016-0443. [PubMed: 28177709].
  • 45. McElroy JF, Wade GN. Short- and long-term effects of ovariectomy on food intake, body weight, carcass composition, and brown adipose tissue in rats. Physiol Behav. 1987;39(3):361-5. [PubMed: 3575476].
  • 46. Vieira-Potter VJ, Padilla J, Park YM, Welly RJ, Scroggins RJ, Britton SL, et al. Female rats selectively bred for high intrinsic aerobic fitness are protected from ovariectomy-associated metabolic dysfunction. Am J Physiol Regul Integr Comp Physiol. 2015;308(6):R530-42. doi: 10.1152/ajpregu.00401.2014. [PubMed: 25608751].
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