Effect of Short-Term Maximal Exercise on Biochemical Markers of Muscle Damage, Total Antioxidant Status, and Homocysteine Levels in Football Players
Asian Journal of Sports Medicine: 3 (4); 239-246
November 30, 2012
Article Type: Research Article
March 20, 2012
May 7, 2012
S, et al. Effect of Short-Term Maximal Exercise on Biochemical Markers of Muscle Damage, Total Antioxidant Status, and Homocysteine Levels in Football Players,
Asian J Sports Med.
Online ahead of Print
Prolonged physical exercise results in transient elevations of biochemical markers of muscular damage. This study examined the effect of short-term maximal exercise on these markers, homocysteine levels (Hcy), and total antioxidant status (TAS) in trained subjects.
Eighteen male football players participated in this study. Blood samples were collected 5-min before and 3-min after a 30-s Wingate test.
The results indicated that plasma biochemical markers of muscle injury increased significantly after the Wingate test ( P<0.05). Moreover, significant increase of white blood Cells and their main subpopulations (i.e. monocytes, neutrophiles, and lymphocytes) ( P<0.001) has been observed. Likewise, uric acid, total bilirubin, and TAS increased significantly after exercise ( P<0.05). However, Hcy levels were unaffected by the Wingate test (for 3-min post-exercise measurement).
Short-term maximal exercise (e.g. 30-s Wingate test) is of sufficient intensity and duration to increase markers of muscle damage, and TAS; but not Hcy levels. Increases in the selected enzymes probably come primarily from muscle damage, rather than liver damage. Moreover, increase of TAS confirms the Wingate test induced oxidative stress.
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