Association of Angiotensin Converting Enzyme gene Polymorphism and Indian Army Triathletes Performance

AUTHORS

Shweta Shenoy , *

How to Cite: Shenoy S. Association of Angiotensin Converting Enzyme gene Polymorphism and Indian Army Triathletes Performance, Asian J Sports Med. Online ahead of Print ; 1(3):34855. doi: 10.5812/asjsm.34855.

ARTICLE INFORMATION

Asian Journal of Sports Medicine: 1 (3); 143-150
Published Online: August 31, 2010
Article Type: Research Article
Received: April 9, 2010
Accepted: July 20, 2010
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Abstract

Purpose: It is well known that the effects of exercise training gives inter individual differences which might be due to genetic diversity. This study aims to explore the probable relation between angiotensin converting enzyme (ACE) alleles and physical fitness parameters in elite athletes.

Methods: Twenty-nine national level Indian Army Triathletes who volunteered for the study were taken as subjects and 101 healthy age matched control group subjects were taken for comparison of genotype frequencies. The following parameters were checked in triathletes: blood pressure, body mass index, VO2 max, muscular endurance, flexibility and power. DNA was extracted from blood using standard phenol-chloroform method. Genotyping was done using PCR specific for ACE (I/D) polymorphism, followed by agarose gel electrophoresis method. Variation of the parameters among different genotypes was compared. Genotype frequencies of triathletes were compared with the control group as well.

Results: No difference was observed between fitness parameters of three genotype groups triathletes, while the frequency of I allele was found to be very high in triathletes compared with the control group.

Conclusion: It can be concluded that there might be a positive association between I allele of ACE gene and endurance.

Keywords

ACE Polymorphism Genetic Angiotensin converting enzyme Physical fitness Genotyping

© 2010, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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